Did you know that many medical professionals are unaware of the MTHFR gene mutation and its implications? Which is quite concerning considering its prevalence.
Thank you Livingwelldallas for the information below!
MTHFR
An estimated 50 percent of the population has one of the 40 variants of MTHFR mutation. And, some MTHFR mutations are more serious than others.
So, are you among the 50 percent? If you are, you probably don’t know it! For instance, most people who have MTHFR mutations don’t experience significant signs, symptoms, or conditions that would lead them to get tested.
How Do Genetics Impact My Health?
Genetics determines more than the color of your hair. Also, genetics can impact your health in several ways. Mutations in genes, even if the mutation is small, underlie susceptibility to many common diseases, including:
•Obesity
•Cancer
•Diabetes
•Mental illness
•Heart disease
The good news is that if you have a gene mutation, the risk of disease can depend on multiple factors that may be in our control.
MTHFR Gene Mutation and Your Health:
MTHFR is an enzyme encoded by the MTHFR gene that makes folic acid usable by the body. A mutation of the MTHFR gene may be linked to serious health conditions, such as:
•Birth abnormalities
•Neurological disorders
•Certain types of cancer
•Mental health disorders
More specifically, researchers have found MTHFR gene mutations can also cause other conditions like:
•Ataxia, a neurological disorder that affects coordination
•Homocysteinemia, abnormally high levels of homocysteine in the blood or urine
•Glaucoma, a group of eye conditions that damage the optic nerve
•Peripheral neuropathy, a neurological condition that affects the nerves
•Scoliosis, the abnormal curvature of the spine
•Microcephaly, a condition in which the head is smaller than usual
•Cardiovascular diseases, such as blood clots, strokes, and heart attacks
•Anemia, a lack of healthy red blood cells
MTHFR Symptoms:
There are three main categories of symptoms or health problems you might encounter with an MTHFR mutation.
1. Cardiovascular
•Elevated homocysteine levels can cause:
•Stroke and heart attack
•Frequent miscarriages
•Congenital birth abnormalities
•Anemia
2. Neurologic
Neurologic conditions that may be caused by an MTHFR mutation include:
•Depression and alcoholism
•Aggression and autism
•Fibromyalgia
•Bipolar disorder and obsessive-compulsive disorder
•Alzheimer’s disease and dementia
•Chronic fatigue syndrome
3. Systemic Intoxication
The build-up of toxic metabolites in the body causes damage to the liver, skin, kidneys, colon, and lungs. This build-up may cause conditions including:
•Nausea, diarrhea, and colon cancer
•Hair loss and rashes
•Rapid heart rate, high blood pressure, and pulmonary fibrosis
•Immune dysfunction
•Kidney and liver dysfunction
Why Do These Symptoms Occur?
The MTHFR enzyme is the controlling enzyme in the production of methyl groups. If an MTHFR gene mutation exists, there will be decreased production of methyl groups resulting in impaired methylation.
Nearly every reaction and function of your involves the process of methylation. Here is a shortlist of the systems and functions that are affected by the methylation process:
》Turning genes on and off
》Detoxifying the body of toxins like chemicals and heavy metals
》Nerve function
》Development of cells in the immune system
》Metabolism and cellular energy production
》Processing and detoxifying hormones
》Building the neurotransmitters that affect mood
》DNA and RNA synthesis
How Do I Know if I Carry a Variant of the MTHFR Gene?
The only way to find out if you have a gene mutation is through genetic testing. There are two different kinds of MTHFR genetic testing.
1. Genetic SNP Testing
To make new cells, an existing cell divides in two, but first, it copies its DNA so the new cell will have its own complete set of genetic instructions.
Mistakes made during this copying process are called SNP errors (single nucleotide polymorphisms). Genetic SNP testing looks for copying errors on your DNA to determine whether you have a gene mutation.
2. Organic Acid Test
This simple urine test looks at biomarkers from various metabolic pathways and analyzes any nutritional deficiencies that might exist.
When specific organic acids are found in organic acid testing, it may signal a metabolic insufficiency, which could be related to:
*Toxicity
*A nutritional deficiency
*A hereditary enzyme deficit
For example, organic acid testing information can lead to significant improvements in numerous other health conditions, including:
▪︎Sleep problems and fatigue
▪︎Mood swings, weight gain, and nausea
▪︎Joint pain, acid reflux, and autoimmune disorders
▪︎Depression, inflammation, and headaches
▪︎Acne/eczema and cancer
Different Variants Have Different Impacts on Health
And, when you get tested, the MTHFR gene will either have zero, one, or two mutations. For instance, the mutations are called variants.
If you have one variant — heterozygous — you are less likely to experience health issues.
If you have two mutations — homozygous — you may have more serious problems.
Gene mutations are inherited from your parents and passed on to your children. At conception, each parent contributes one copy of the MTHFR gene to the baby. Lastly, if both parents have mutations, the risk of the child having a homozygous mutation is higher.
Managing MTHFR:
To clarify, managing MTHFR is as complex as every individual is unique. And, the number and type of MTHFR mutations significantly affect the approach to and outcome of care.
In short, genetics cannot be changed, but how genes behave can. And, a comprehensive approach that combines diet and lifestyle changes to support proper and efficient methylation can effectively treat MTHFR. However, there is no one-size-fits-all approach.
PLEASE NOTE: The content, ideas, and views in this article are those of the presenter(s); Arvesa does not claim ownership of the content or the information provided above. Arvesa’s intention in sharing information is to provide access to said information so that viewers may come to their own informed conclusion(s).
FAIR-USE COPYRIGHT DISCLAIMER: Copyright Disclaimed under Section 107 of the Copyright Act 1976, allowance is made for “fair use” for purposes such as criticism, commenting, news reporting, teaching, scholarship and research. Fair use, including that of educational or personal use, is a use as permitted by copyright statute. Arvesa has uploaded this information as to preserve its integrity for educational purposes. Therefore, the use of material in this post constitutes a ‘FAIR USE’ of any such copyrighted material; the martial in this article is for research and educational purposes only.